Comparison of Second- and Third-Generation Enzyme Immunoassays for Detecting Antibodies to Hepatitis C Virus

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Comparison of second- and third-generation enzyme immunoassays for detecting antibodies to hepatitis C virus.

Supplemental assays, such as recombinant immunoblot assays (RIBA), are used to confirm detection of antibodies to hepatitis C virus (HCV). However, due to their expense, they are not widely used in developing countries. The purpose of our study was to compare the results of second- and third-generation (G2 and G3, respectively) enzyme immunoassays (EIAs) and to resolve discordant results by usi...

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Peptide based enzyme immunoassays for detecting hepatitis C antibodies in sera of people at high risk.

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Enzyme immunoassays for anti-hepatitis C virus antibodies improved specificity and analytical sensitivity by combination of three different recombinant viral proteins in second generation tests.

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Departamento de Clínica Médica, Universidade Federal de Mato Grosso, Rua L s/ no, 78070-000 Cuiabá, MT, Brasil *Fundação Nacional de Saúde, Av. Getúlio Vargas 867, 78045-720 Cuiabá, MT, Brasil **Departamento de Virologia, Instituto Oswaldo Cruz, Av. Brasil 4365, 21045-900 Rio de Janeiro, RJ, Brasil ***Hospital Prof. Edgar Santos, Universidade Federal da Bahia, Rua João das Botas s/ no, 40110-16...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2002

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.40.5.1656-1659.2002